I-Tiamulin Hydrogen Fumarate
I-Tiamulin hydrogen fumarate
I-Tiamulin hydrogen fumarate iphuma ku-pleuromutilin, ingasetshenziswa ekwelashweni kwezilwane ikakhulukazi ezingulubeni nasezinkukhuni.Iyi-diterpene antimicrobial enamakhemikhali e-pleuromutilin afana nalawo e-valnemulin.
I-Tiamulin hydrogen fumarate imhlophe noma icishe ibe mhlophe njenge-crystalline powder, ayinaphunga futhi ayinambitheki.Incibilika kalula ku-methanol noma ku-ethanol, inyibilika emanzini, incibilika kancane ku-acetone, futhi icishe ingancibiliki ku-hexane.
Indlela yesenzo nezici
Lo mkhiqizo uyi-bacteriostatic antibiotic, kodwa futhi unomphumela we-bactericidal kuma-bacterium azwelayo ekugxilweni okuphezulu kakhulu.Indlela yokusebenza ye-antibacterial ukuvimbela ukuhlanganiswa kwamaprotheni ebhaktheriya ngokubophezela kuyunithi ye-50s ye-ribosome yebhaktheriya.
I-Tiamulin hydrogen fumarate inomsebenzi omuhle wokulwa namagciwane ngokumelene nezinhlobonhlobo ze-Gram-positive cocci, kuhlanganise neningi le-staphylococci ne-streptococci (ngaphandle kwe-group D streptococci) kanye nezinhlobonhlobo ze-mycoplasmas namanye ama-spirochetes.Kodwa-ke, umsebenzi wokulwa namagciwane ngokumelene namagciwane athile angalungile awunamandla kakhulu, ngaphandle kwezinhlobo ze-Haemophilus nezinye izinhlobo ze-E. coli ne-Klebsiella.
I-Tiamulin hydrogen fumarate kulula ukumunca ngemva kokuphathwa ngomlomo ezingulubeni.Cishe u-85% womthamo owodwa uyamuncwa, futhi ukugxila okuphezulu kwenzeka emahoreni ama-2 kuye kwamane.Kusatshalaliswa kakhulu emzimbeni, ngokugxila okuphezulu kakhulu emaphashini.I-Tiamulin hydrogen fumarate igaywa emzimbeni ibe ama-metabolites angama-20, amanye anokuzola kwe-antibacterial.Cishe u-30% wama-metabolites akhishwa emchameni bese kuthi ingxenye esele ikhishelwe endle.
Ukusetshenziswa
I-Tiamulin hydrogen fumarate isetshenziselwa ukwelapha inyumoniya ezingulubeni ebangelwa i-Actinobacillus pleuropneumoniae kanye nesifo sohudo segazi lezingulube esibangelwa i-Treponema hyodysenteriae.Njengesengezo sesidakamizwa sokuphakelayo sezingulube singakhuthaza ukuzuza kwesisindo.Iphinde isebenze ngokumelene nesifo sokuphefumula esingapheli ezinkukhu, i-mycoplasma hyopneumonia, kanye ne-staphylococcal synovitis ezinkukhu.
Okuqukethwe
≥ 98%
Ukucaciswa
USP42/ EP10
Ukupakisha
25kg/isigubhu sekhadibhodi
Amalungiselelo
10%, 45% 80% Tiamulin hydrogen fumarate premix / powder encibilikayo
I-Hebei Veyong Pharmaceutical Co., Ltd, yasungulwa ngo-2002, etholakala eShijiazhuang City, eSifundazweni saseHebei, eChina, eduze kweNhloko-dolobha yaseBeijing.Uyibhizinisi elikhulu lemithi yezilwane eqinisekiswe yi-GMP, ene-R&D, ukukhiqizwa nokudayiswa kwama-API wezilwane, amalungiselelo, okuphakelayo okuxutshwe ngaphambili nezithasiselo zokudla.NjengeSikhungo Sezobuchwepheshe Sesifundazwe, i-Veyong isungule uhlelo olusha lwe-R&D lomuthi omusha wezilwane, futhi iyibhizinisi lezobuchwepheshe elaziwa kuzwelonke elisekelwe kudokotela wezilwane, kunochwepheshe abangama-65.I-Veyong inezisekelo ezimbili zokukhiqiza: i-Shijiazhuang ne-Ordos, lapho isisekelo se-Shijiazhuang sihlanganisa indawo engu-78,706 m2, nemikhiqizo ye-API engu-13 ehlanganisa i-Ivermectin, i-Eprinomectin, i-Tiamulin Fumarate, i-Oxytetracycline hydrochloride ects, kanye ne-11, imigqa yokukhiqiza ye-powder yokulungiselela , premix, bolus, izibulala-zinambuzane nesibulala-magciwane, njll.I-Veyong ihlinzeka ngama-API, amalungiselelo angaphezu kwe-100 elebula uqobo, kanye nesevisi ye-OEM & ODM.
I-Veyong ibheka ukubaluleka okukhulu ekuphathweni kohlelo lwe-EHS(Imvelo, Impilo Nokuphepha), futhi yathola izitifiketi ze-ISO14001 ne-OHSAS18001.I-Veyong isohlwini lwamasu amabhizinisi ezimboni asafufusa esifundazweni sase-Hebei futhi ingaqinisekisa ukuhlinzekwa okuqhubekayo kwemikhiqizo.
I-Veyong yasungula uhlelo oluphelele lokuphatha ikhwalithi, yathola isitifiketi se-ISO9001, isitifiketi se-China GMP, isitifiketi se-APVMA GMP yase-Australia, isitifiketi se-Ethiopia GMP, isitifiketi se-Ivermectin CEP, futhi yaphumelela ukuhlolwa kwe-US FDA.I-Veyong inethimba elichwepheshile lokubhalisa, ukuthengisa kanye nenkonzo yezobuchwepheshe, inkampani yethu ithole ukwethenjwa nokusekelwa kumakhasimende amaningi ngekhwalithi yomkhiqizo omuhle kakhulu, ikhwalithi ephezulu yokuthengisa kwangaphambili kanye nenkonzo yangemuva kokuthengisa, ukuphathwa okungathi sína nokwesayensi.I-Veyong yenze ukubambisana kwesikhathi eside namabhizinisi amaningi emithi yezilwane aziwa emhlabeni wonke ngemikhiqizo ethunyelwa eYurophu, eNingizimu Melika, eMpumalanga Ephakathi, e-Afrika, e-Asia, njll. emazweni nasezifundeni ezingaphezu kuka-60.