I-30% Florfenicol Ukujova
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Isenzo samakhemisi
IFlorfenicol iyi-antibiotic ebanzi ye-antibiotic ye-Amide Alcohol kanye ne-bacteriostatic ejenti. Isebenza ngokubopha i-subunit yama-50s ye-ribosome ukuvimbela ukuhlanganiswa kwamaprotheni amagciwane. Inomsebenzi oqinile we-antibacterial ngokumelene namagciwane ahlukahlukene ama-gram nama-gram-amabi. Capeteurella hemolyticus, pasteurella multrocida ne-ActInobacillus Pleuropneumoniae bazwela kakhulu eFlorfenicol. Umsebenzi we-antibacterial weFlorfenicol ngokumelene nama-microorganisms amaningi e-vitro uyafana noma unamandla kunalokho kweThiamphenicol. Amanye ama-bacteria amelana notshwala obukhona ngenxa ye-acetylation, njenge-Escherhia Coli naseKlebsiella pneumoniae, kusengamelana ne-fluorobenzeene. UNico uyazwela. Isetshenziselwa ikakhulukazi izifo zamagciwane ezingulube, izinkukhu nenhlanzi ebangelwa amagciwane abucayi, njengezifo zokuphefumula zezinkomo nezingulube ezibangelwa yi-pasteurella hemolyticus, pasteurella multocida ne-Actinobacillus Pleuropneoniae. I-Salmonella ebangelwa yi-typhone fever kanye ne-paratyphoid Fever, Cholera yenkukhu, inkukhu Pooleram, i-Colibacilsosis, njll.; I-Fish Bacterial Sepsis ebangelwa yizinhlanzi pasteurella, vibrio, staphylococcus aureus, hydrophila, entertidis, njll. Entertitis, Isikhumba Esibomvu Skin, njll.
Pharmacokinetics
IFlorfenicol idonswa ngokushesha ukuphathwa ngomlomo, kanti ukugxilwa kwezokwelapha kungafinyelelwa egazini ngemuva kwehora elingu-1, futhi ukugxila kwegazi eliphakeme kungafinyelelwa kungakapheli amahora angu-1 kuye kwayi-3. I-Bioavailability ingaphezulu kwama-80%. IFlorfenicol isatshalaliswa kabanzi ezilwaneni futhi ingangena ngesithiyo segazi-ubuchopho. Ifakwe ikakhulu kumchamo ngendlela yayo yasekuqaleni, futhi inani elincane likhishwe ku-feeces.
Isenzo nokusetshenziswa
Amidol antibiotic. Kwama-pasteurella kanye ne-E. Coli izifo.
Umthamo nokuphatha
Ukujova kwe-intramuscular: umthamo owodwa, u-0.067 ml wezinkukhu kanye no-0.05 ~ 0.067 ml wezingulube nge-1 kg isisindo somzimba. Njalo emahoreni angama-48 ngemithamo emi-2. Izinhlanzi 0.0017 ~ 0.0034ml, QD.
Ukuphendula Okubi
1.I-30% Florfenicol Ukujovainomphumela othile we-immunosuppresprespressive uma isetshenziswa kuma-doses aphezulu kunethamo elinconyiwe.
2. Inombritoxicity futhi kufanele isetshenziswe ngokuqapha emfuyweni ngesikhathi sokukhulelwa kanye ne-lactation.
Izinyathelo zokuzivikela:
1. Kuhlanganiswe ekubekeni izinkukhu ngesikhathi sokubeka.
2. Kuhlanganiswe ngesikhathi sokugoma noma ezilwaneni ezinomsebenzi wokuzivikela komzimba.
I-3. Ukuncishiswa kwethamo elifanelekile noma ukunwebeka kwesikhawu se-dosing kuyadingeka ezilwaneni ezithintekile ngokuphefumula kwe-renal.
Isikhathi sokuhoxisa
Ingulube 14 izinsuku, izinsuku zenkukhu ezingama-28.
UHebei Veyong Pharmaceutical Co, Ltd, wasungulwa ngonyaka ka-2002, etholakala eShijiazhuang City, esifundeni saseHebei, eChina, eduze kwenhloko-dolobha eBeijing. Uyibhizinisi elikhulu lezidakamizwa eliqinisekisiwe le-GMP, nge-R & D, ukukhiqizwa kanye nokuthengiswa kwama-apis wezilwane, amalungiselelo, okuphakelayo okubekiwe kanye nokuphakelwa izengezo. Njengesikhungo sezobuchwepheshe sesifundazwe, uVeyong usungule uhlelo olusha lwe-R & D lwe-New Veterinary Drug, futhi yiwona we-technological annology ebhizinisini elisuselwa kubuchwepheshe, kukhona ochwepheshe bezobuchwepheshe abangama-65. UVeyong unezisekelo ezimbili zokukhiqiza: I-Shijuazhuang kanye ne-Ordos, lapho iShijuazhuange isiza ifaka indawo engu-78,706 m2, i-Oxytetracycline imigqa yokukhiqiza kubandakanya i-ivermectin, i-olytetracycline imigqa yokukhiqiza kubandakanya umjovo, i-bolus, ama-pesticides kanye amagciwane, amahlelo. UVeyong unikeza ama-API, amalungiselelo angaphezu kwe-100 anamalebula, kanye nensizakalo ye-OEM & ODM.
UVeyong unamathela ngokubaluleka okukhulu ekuphathweni kwe-EHS (imvelo, ezempilo kanye nokuphepha), futhi uthole izitifiketi ze-ISO14001 nezi- ohsas180000. UVeyong ubhalwe phansi kumabhizinisi wezimboni asafufusa izimboni esifundazweni saseHebei futhi angaqinisekisa ukunikezwa kwemikhiqizo okuqhubekayo.
UVeyong wasungula uhlelo oluphelele lokuphathwa kwekhwalithi, ethola isitifiketi se-ISO9001, isitifiketi se-China GMP, isitifiketi se-APHVMA GMP, isitifiketi se-Ethiopia GMP, isitifiketi se-Ivermectin CEP, futhi sadlula ukuhlolwa kwe-US FDA. UVeyong uneqembu eliqeqeshiwe lokurejista, ukuthengisa kanye nenkonzo yezobuchwepheshe, inkampani yethu ithole ukuthembela nokusekelwa okuvela kumakhasimende amaningi ngekhwalithi ephezulu yomkhiqizo, insizakalo ephezulu yokuthengisa kanye nokuthengisa okuthengiswayo, ukuphathwa okungathi sína. UVeyong wenze ukubambisana isikhathi eside ngamabhizinisi amaningi ezaziwayo ezingezemikhiqizo athunyelwe eYurophu, eSouth America, eMpumalanga Ephakathi, e-Eshiya, e-ESIA, amazwe angaphezu kwangu-60.
