I-20% u-Albendazole Granule
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I-Pharmacology
I-Albendazole iyisisulwa se-benzimidazole, esingahlanganiswa ngokushesha emzimbeni ukuze sibe se-sulfoxide, i-sulfone alcohol kanye notshwala ezi-2-aminOsulfone. Ikhetha futhi ngokungakhethi ivimbela i-polymerization yohlelo lwe-cytoplasmic microtubule lwamaseli odongeni lwamathumbu wamathumbu wamathumbu amathumbu, futhi angavimba ukunakekelwa kwe-glycogen okuhlukahlukene ezinambuzaneni, futhi angavimba ukuncishiswa kwe-endosogen kwizinambuzane I-Triphosphate futhi ivimbela ukusinda nokuzalwa kabusha kwesibungu. Ifana ne-Mebendazole, lo mkhiqizo ungadala nokuwohloka kwama-cytoplasmic microtubule amaseli amathumbu wesibungu, abumbe i-tubulin ye-tubulin, okubangela ukuncishiswa kwezinto zokuhamba nge-golgi endocrine, i-cytoplasmic disoderal, nokuwohloka okuphelele kwamaseli amuncwa. Kubangela ukufa kwesibungu.I-20% u-Albendazole GranuleUngabulala ngokuphelele amaqanda we-hookworm namaqanda we-whipworm futhi ngokwengxenye ukubulala amaqanda we-roundworm. Ngaphezu kokubulala nokuxosha ama-nematode ahlukahlukene ahlukahlukene ezilwaneni, futhi unokubulawa okusobala nokukhipha imiphumela kuma-tapeworms naseCysticeCus.
Ubunzisi
Ukuhlolwa kobuthi kukhombisa ukuthi lo mkhiqizo unobuthi obuphansi futhi uphephile. I-Oral LD50 yamagundane inkulu kune-800mg / kg, kanye nethamo eliphakeme kakhulu lezinja lingaphezu kuka-400mg / kg. Lesi sidakamizwa asinamthelela ekusebenzeni kokuzala kwamagundane abesilisa, futhi awunawo umphumela we-teratogenic kumagundane abesifazane. Ukutholwa kwe-fetus kungenzeka kungenzeka lapho umthamo omkhulu [30 mg / (㎏: Kanye nokukhubazeka kwamathambo.
Ukusetshenziswa kanye Dosage
Kususelwa ku-Albindazole. Ukuphathwa ngomlomo: kanye, isisindo somzimba esingu-25 ~ 50mg / kg. Noma ulandele izeluleko zikadokotela.
Ukuphendula Okubi
(1) Lapho izinja zinikezwa ama-50 mg / kg kabili ngosuku, kancane kancane bazothuthukisa i-anorexia
(2) Ukusetshenziswa kwe-Albindazole ekukhulelweni kusenesikhathi kungahambisana ne-teratogenicity kanye nombryotoxity.
Incwajana
Izilwane kufanele ziqaphele ezinsukwini zokuqala ezingama-45 ngemuva kokukhulelwa
UHebei Veyong Pharmaceutical Co, Ltd, wasungulwa ngonyaka ka-2002, etholakala eShijiazhuang City, esifundeni saseHebei, eChina, eduze kwenhloko-dolobha eBeijing. Uyibhizinisi elikhulu lezidakamizwa eliqinisekisiwe le-GMP, nge-R & D, ukukhiqizwa kanye nokuthengiswa kwama-apis wezilwane, amalungiselelo, okuphakelayo okubekiwe kanye nokuphakelwa izengezo. Njengesikhungo sezobuchwepheshe sesifundazwe, uVeyong usungule uhlelo olusha lwe-R & D lwe-New Veterinary Drug, futhi yiwona we-technological annology ebhizinisini elisuselwa kubuchwepheshe, kukhona ochwepheshe bezobuchwepheshe abangama-65. UVeyong unezisekelo ezimbili zokukhiqiza: I-Shijuazhuang kanye ne-Ordos, lapho iShijuazhuange isiza ifaka indawo engu-78,706 m2, i-Oxytetracycline imigqa yokukhiqiza kubandakanya i-ivermectin, i-olytetracycline imigqa yokukhiqiza kubandakanya umjovo, i-bolus, ama-pesticides kanye amagciwane, amahlelo. UVeyong unikeza ama-API, amalungiselelo angaphezu kwe-100 anamalebula, kanye nensizakalo ye-OEM & ODM.
UVeyong unamathela ngokubaluleka okukhulu ekuphathweni kwe-EHS (imvelo, ezempilo kanye nokuphepha), futhi uthole izitifiketi ze-ISO14001 nezi- ohsas180000. UVeyong ubhalwe phansi kumabhizinisi wezimboni asafufusa izimboni esifundazweni saseHebei futhi angaqinisekisa ukunikezwa kwemikhiqizo okuqhubekayo.
UVeyong wasungula uhlelo oluphelele lokuphathwa kwekhwalithi, ethola isitifiketi se-ISO9001, isitifiketi se-China GMP, isitifiketi se-APHVMA GMP, isitifiketi se-Ethiopia GMP, isitifiketi se-Ivermectin CEP, futhi sadlula ukuhlolwa kwe-US FDA. UVeyong uneqembu eliqeqeshiwe lokurejista, ukuthengisa kanye nenkonzo yezobuchwepheshe, inkampani yethu ithole ukuthembela nokusekelwa okuvela kumakhasimende amaningi ngekhwalithi ephezulu yomkhiqizo, insizakalo ephezulu yokuthengisa kanye nokuthengisa okuthengiswayo, ukuphathwa okungathi sína. UVeyong wenze ukubambisana isikhathi eside ngamabhizinisi amaningi ezaziwayo ezingezemikhiqizo athunyelwe eYurophu, eSouth America, eMpumalanga Ephakathi, e-Eshiya, e-ESIA, amazwe angaphezu kwangu-60.
