20% Florfenicol WSP
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Ividiyo
I-Pharmacodynamics
I-Flofenicol iyimithi elwa namagciwane ene-spectrum ebanzi ye-amide kanye ne-bacteriostatic ejenti, esebenza ngokuvimbela ukuhlanganiswa kwamaprotheni ebhaktheriya ngokubophezela ku-50S subunit ye-ribosome.Inomsebenzi oqinile we-antibacterial ngokumelene nezinhlobonhlobo zamagciwane e-gram-positive kanye ne-gram-negative.I-Pasteurella hemolytica, i-Pasteurella multocida, ne-Actinobacillus pleuropneumoniae zisengozini enkulu ye-florfenicol.Umsebenzi we-antibacterial we-florfenicol ngokumelene nama-microorganisms amaningi e-vitro ufana noma unamandla kunalowo we-thiamphenicol, futhi amanye amagciwane amelana ne-amide alcohols ngenxa ye-acetylation, njenge-Escherichia coli ne-Klebsiella pneumoniae, asengase Azwele ku-florfenicol.
Isetshenziselwa ikakhulukazi izifo ezibangelwa amagciwane ezingulube, izinkukhu nezinhlanzi ezibangelwa amagciwane azwelayo, njengezifo zokuphefumula zezinkomo nezingulube ezibangelwa i-Pasteurella hemolytica, i-Pasteurella multocida ne-Actinobacillus pleuropneumoniae.I-typhoid fever kanye ne-paratyphoid fever ebangelwa i-Salmonella, ikholera yenkukhu, i-pullorum, i-Escherichia coli, njll;amagciwane ezinhlanzi ezibangelwa i-Pasteurella, Vibrio, Staphylococcus aureus, Hydromonas, Enteritidis, njll. I-Sepsis, i-enteritis, isifo sesikhumba esibomvu, njll.
I-Pharmacokinetics
Ukuphathwa ngomlomo kwe-florfenicol kungena ngokushesha, futhi ukugxila kokwelapha kungafinyelelwa egazini ngemuva kwehora eli-1, futhi ukugcwala okukhulu kwegazi kungafinyelelwa emahoreni angama-1 kuye kwayi-3.I-bioavailability ingaphezu kwama-80%.I-Flofenicol isatshalaliswa kabanzi ezilwaneni futhi ingadlula kumgoqo wegazi nobuchopho.Ikhishwa ngokuyinhloko ngendlela yokuqala emchameni, futhi inani elincane likhishwa ngendle.
Ukusebenzisana kwezidakamizwa
(1) Ama-Macrolides nama-lincosamide anomgomo ofanayo wokusebenza njengalo mkhiqizo, womabili abophezelekile ku-50S subunit ye-ribosome yebhaktheriya, futhi angaveza ukuphikisa lapho esetshenziswa ngokuhlangene.(2) Kungase kungqubuzane nomsebenzi wokubulala amagciwane wama-penicillin noma ama-aminoglycosides, kodwa akuzange kuboniswe ezilwaneni.
Isenzo nokusetshenziswa
I-Amide alcohol antibiotics.Ngezifo ze-Pasteurella ne-Escherichia coli.
Ukusetshenziswa kanye Nesilinganiso
Ngokusekelwe kulo mkhiqizo.Ukuphatha ngomlomo: nge-1kg yesisindo somzimba, 0.1 ~ 0.15g yezingulube nezinkukhu.Izikhathi ezi-2 ngosuku izinsuku ezi-3 kuye kwezi-5.Inhlanzi 50 ~ 75mg.Isikhathi esingu-1 ngosuku izinsuku ezi-3 kuye kwezi-5.
Ukusabela okubi
I-20% i-Florfenicol powder encibilikayo yamanzi inomphumela othile we-immunosuppressive uma isetshenziswe ngesilinganiso esiphezulu kunomthamo onconywayo.
Ukunaka
(1) Izinkukhu ezizalela amaqanda ukuze zidliwe abantu akufanele zisetshenziswe ngesikhathi sokuzalela;(2) Sebenzisa ngokuqapha kubafuyi.Ine-embryotoxicity futhi kufanele isetshenziswe ngokuqapha emfuyweni ekhulelwe neyamunyisayo;(3) It is contraindicated ngesikhathi sokugoma noma ezilwaneni ezinzima immunodeficiency;(4) Ezilwaneni ezinokwehluleka kwezinso, umthamo kufanele wehliswe ngokufanelekile noma isikhathi somthamo kufanele sinwetshwe.
Isikhathi sokuhoxa
Izinsuku ezingu-20 zezingulube, izinsuku ezingu-5 zezinkukhu;Izinsuku ezingama-375 degree zezinhlanzi.
Isitoreji
Gcina kuvaliwe futhi endaweni eyomile
I-Hebei Veyong Pharmaceutical Co., Ltd, yasungulwa ngo-2002, etholakala eShijiazhuang City, eSifundazweni saseHebei, eChina, eduze kweNhloko-dolobha yaseBeijing.Uyibhizinisi elikhulu lemithi yezilwane eqinisekiswe yi-GMP, ene-R&D, ukukhiqizwa nokudayiswa kwama-API wezilwane, amalungiselelo, okuphakelayo okuxutshwe ngaphambili nezithasiselo zokudla.NjengeSikhungo Sezobuchwepheshe Sesifundazwe, i-Veyong isungule uhlelo olusha lwe-R&D lomuthi omusha wezilwane, futhi iyibhizinisi lezobuchwepheshe elaziwa kuzwelonke elisekelwe kudokotela wezilwane, kunochwepheshe abangama-65.I-Veyong inezisekelo ezimbili zokukhiqiza: i-Shijiazhuang ne-Ordos, lapho isisekelo se-Shijiazhuang sihlanganisa indawo engu-78,706 m2, nemikhiqizo ye-API engu-13 ehlanganisa i-Ivermectin, i-Eprinomectin, i-Tiamulin Fumarate, i-Oxytetracycline hydrochloride ects, kanye ne-11, imigqa yokukhiqiza ye-powder yokulungiselela , premix, bolus, izibulala-zinambuzane nesibulala-magciwane, njll.I-Veyong ihlinzeka ngama-API, amalungiselelo angaphezu kwe-100 elebula uqobo, kanye nesevisi ye-OEM & ODM.
I-Veyong ibheka ukubaluleka okukhulu ekuphathweni kohlelo lwe-EHS(Imvelo, Impilo Nokuphepha), futhi yathola izitifiketi ze-ISO14001 ne-OHSAS18001.I-Veyong isohlwini lwamasu amabhizinisi ezimboni asafufusa esifundazweni sase-Hebei futhi ingaqinisekisa ukuhlinzekwa okuqhubekayo kwemikhiqizo.
I-Veyong yasungula uhlelo oluphelele lokuphatha ikhwalithi, yathola isitifiketi se-ISO9001, isitifiketi se-China GMP, isitifiketi se-APVMA GMP yase-Australia, isitifiketi se-Ethiopia GMP, isitifiketi se-Ivermectin CEP, futhi yaphumelela ukuhlolwa kwe-US FDA.I-Veyong inethimba elichwepheshile lokubhalisa, ukuthengisa kanye nenkonzo yezobuchwepheshe, inkampani yethu ithole ukwethenjwa nokusekelwa kumakhasimende amaningi ngekhwalithi yomkhiqizo omuhle kakhulu, ikhwalithi ephezulu yokuthengisa kwangaphambili kanye nenkonzo yangemuva kokuthengisa, ukuphathwa okungathi sína nokwesayensi.I-Veyong yenze ukubambisana kwesikhathi eside namabhizinisi amaningi emithi yezilwane aziwa emhlabeni wonke ngemikhiqizo ethunyelwa eYurophu, eNingizimu Melika, eMpumalanga Ephakathi, e-Afrika, e-Asia, njll. emazweni nasezifundeni ezingaphezu kuka-60.
